合肥地区唐氏综合征筛查中位数方程的研究 许晓红;刘辉;黄大雁;李子贤;邓松华 【期刊名称】《安徽医科大学学报》 【年(卷),期】2014(000)001 【摘 要】目的以数据分析软件拟合合肥地区孕中期母血清标志物中位数方程，并评价新方程的效果。方法取合肥地区33638例孕妇的产前筛查数据，以SPSS 17.0拟合新中位数方程，比较新中位数与2T-Risk软件内嵌中位数，计算风险结果，比较筛查效率。结果新中位数方程与内嵌中位数有差异，更换中位数后，筛查效率提高。结论用数据分析软件拟合本实验室中位数方程可以提高筛查效率，此中位数方程对合肥地区产前筛查有指导意义。%Objective To detect the median equation of maternal serum markers with second trimester gestation in Hefei, and to evaluate the effect of the new equation. Methods The maternal serum markers of 33 638 women were involved in this study. The new median equation was calculated through SPSS 17.0 and the difference between new median and data of 2T-risk were also evaluated. The individual risk assessment was established to verify antep-artum risk screening results. Results The new median equation was superior to data of 2T-risk which effectively reduced the birth defects. Conclusion Screening efficiency can be improved by re-calculation of median, and the new median equation has very important significance to the prenatal screening in Hefei. 【总页数】4页(P47-50) 【作 者】许晓红;刘辉;黄大雁;李子贤;邓松华 【作者单位】安徽省妇幼保健院检验科，合肥 230001;安徽省妇幼保健院检验科，合肥 230001;安徽省妇幼保健院检验科，合肥 230001;安徽省妇幼保健院检验科，合肥 230001;安徽医科大学病理生理学教研室，合肥 230032 【正文语种】中 文 【中图分类】R714.55 【相关文献】 1.唐氏综合征产前筛查指标中位数倍数值中位数监测和质量评价方法的应用分析 [J], 蒋宇林;刘俊涛;刘善英;郝娜;周京;戚庆炜;周希亚;边旭明 2.唐氏综合征产前筛查指标中位数倍数值中位数的监测和质量评价方法 [J], 蒋宇林;刘俊涛;边旭明 3.建立天津地区孕中期唐氏综合征筛查人群中位数系统的研究 [J], 姚静怡;张颖;辛力;崔岚;岳胜;谢晓媛 4.岳阳地区唐氏综合征筛查中位数参数本地化研究 [J], 邬洪梁;祝群;邵志兵;谢杰;冯丹;蔡薇 5.唐氏综合征产前筛查室内批间变异对中位数倍数值中位数的影响 [J], 龚智仁;黄平;刘在栓 因版权原因，仅展示原文概要，查看原文内容请购买 本文来源：https://www.wddqw.com/doc/47ff9b5f51d380eb6294dd88d0d233d4b14e3fb2.html